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The Patent Office Journal 17/12/2010
4596
(12) PATENT APPLICATION PUBLICATION (21) Application No.3988/CHENP/2010 A
(19) INDIA
(22) Date of filing of Application :28/06/2010 (43) Publication Date : 17/12/2010
(54) Title of the invention : CELL ASSAY KIT AND METHOD
(51) International classification :C12Q1/06
(31) Priority Document No :60/992,624
(32) Priority Date :05/12/2007
(33) Name of priority country :U.S.A.
(86) International Application No
Filing Date
:PCT/US08/085737
:05/12/2008
(87) International Publication No
:WO 2009/076235
A2
(61) Patent of Addition to Application
Number
Filing Date
:NA
:NA
(62) Divisional to Application Number
Filing Date
:NA
:NA
(71)Name of Applicant :
1)ZYOMYX INC
Address of Applicant :26101 RESEARCH ROAD
HAYWARD,CA 94545. U.S.A.
(72)Name of Inventor :
1)ZUAGG FRANK
2)TOBIAS RENEE
3)KERNEN PETER
4)RUIZ TAYLOR,LAURENCE
5)WAGNER PETER
(57) Abstract :
A method and kit for assaying a cell sample for the presence of at least a threshold number of cells of a given type are disclosed. The
kit includes an assay device having a sample chamber for receiving the cell sample and an elongate collection chamber containing a
selected- density and/or viscosity medium and having along its length, a plurality of cell-collection regions, and particles which are
capable of specific attachment to cells of the selected cell type, and which are effective, when attached to the cells, to increase the
density or magnetic susceptibility of the cells. In operation, particle-bound cells and particles in the cell sample are drawn through the
elongate collection chamber under the influence of a gravitational or selected centrifugal or magnetic-field force until the particle-
bound cells and particles completely fill successive cell- collection regions in the collection chamber. Indicia associated with at least
one collection regions indicates a concentration of cells of the selected type effective to at least partially fill that collection region.
No. of Pages : 46 No. of Claims : 35
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